FDA approved international key Phase III clinical trial scheme on XNW4107 developed by Evopoint for indications of HAP/VAP in April 2022
XNW4107 is a β-lactamase
inhibitor with independent intellectual property rights owned by Evopoint. It
has excellent antibacterial activities when combining with Imipenem and
Cilastatin (β-lactam antibiotics) against carbapenem-resistant bacterial infections
that has an increased incidence in recent years, such as carbapenem-resistant
Acinetobacter baumannii (CRAB), carbapenem-resistant Pseudomonas aeruginosa
(CRPA), carbapenem-resistant Enterobacteriaceae (CRE), etc.